Chemistry 360 -- Essentials of Biochemistry

Tentative Lecture Schedule -- Spring 2000

This schedule is laid out in the following format:
Date: Reading Assignment (sections or pages)
Topics covered (sections or pages)

1/12/00: introduction, §1.3, §1.4
        Course Introduction
        What is Biochemistry? p.xxv-xxvii
        Special Considerations of Biochemistry p.xxv-xxvii
        Elements p.not really in book
        Classes of Molecules p.7
        Water p.10-12
        Intermolecular forces p.18-21

1/13/00 (discussion)
Lab notebooks
Experiments
Methods

1/13/00 (lab)
Check out equipment
Safety information

1/14/00: §1.2, §1.3
pH, Buffers and the Henderson-Hasselbach equation p.12-18
Cell Structure p.8-10

1/17/00
No Class :(

1/19/00: §5.1
Monosaccharides p.117-125

1/20/00 (discussion)
Experiment 301 prelab

1/20/00 (lab)
Experiment 301

1/21/00: §5.2, 5.3
Reactions of Monosaccharides p.125-126
Disaccharides p.126-128

1/24/00: §5.4, 5.5
Polysaccharides p.128-137

1/26/00: §6.1, 6.2
Functions of Lipids
Structural Lipids p.141-148

1/27/00 (discussion)
Experiment 301 prelab
Quiz 2

1/27/00 (lab)
Experiment 301

1/28/00: §6.3, 6.4
Other lipids p.150-156

1/31/00: §6.5, 6.6
Membrane Structure and Function p.156-163

2/2/00: §2.1
Amino Acid Structure

2/3/00 (discussion)
Experiment 301 prelab

2/3/00 (lab)
Quiz 3
Experiment 301

2/4/00: §2.2
Amino Acid Chemistry

2/7/00: §2.3-2.5
Peptide Bond
Important Peptides

2/9/00
Exam 1: Chapters 1, 2, 5 and 6

2/10/00 (discussion)
Quiz
Experiment 302 prelab

2/10/00 (lab)
Experiment 302

2/11/00: §3.1
Protein Classification

2/14/00: §3.2, 3.6
Protein Primary Structure

2/16/00: §3.3, 3.6
Protein Secondary Structure

2/17/00 (discussion)
Quiz
Experiment 302 prelab

2/17/00 (lab)
Experiment 302

2/18/00: §3.5
Protein Tertiary, Quaternary Structure

2/21/00: §4.1, 4.2
Enzyme Classification

2/23/00: §4.4
Coenzymes

2/24/00 (discussion)
Quiz
Experiment 303 prelab

2/24/00 (lab)
Experiment 303

2/25/00: §Chapter 4
Enzyme Kinetics

2/28/00: §Chapter 4
Enzyme Active Sites

3/1/00: §Chapter 4
Enzyme Regulation

3/2/00 (discussion)
Quiz
Experiment 303 prelab

3/2/00 (lab)
Experiment 303

3/3/00: §7.1-7.4
Nucleic Acid Structure

3/6/00: §7.5, 7.6
Nucleic Acid Properties

3/8/00
Exam 2: Chapters 3, 4 and 7

3/9/00 (discussion)
Quiz
Experiment 303 prelab

3/9/00 (lab)
Experiment 303

3/10/00: §Chapters 8 and 9
        Overview of Metabolism
        Basics of Thermodynamics and Coupled reactions
        Types of Pathways

3/13/00: §10.1-10.3 Glycolysis
        Importance and location
        Reactions
        Regulation
        Energetics
        Fates of pyruvate

3/15/00: §11.1, 11.3 Krebs Cycle
        Importance and location
        Reactions
        Regulation

3/16/00 (discussion)
Quiz
Experiment 305 prelab

3/16/00 (lab)
Experiment 305

3/17/00: §11.4, 11.5 Krebs Cycle
        Energetics
        Mitochondrial Transporters
        Glyoxylate cycle

3/20-3/26: Spring Break
Draw out the Krebs cycle in suntan lotion on the back of your 'partner' on the beach

3/27/00: §12.3-12.5
        Electron transport chain
        Oxidative phosphorylation
        Evidence for the chemiosmotic mechanism

3/29/00: §13.3
        ß-oxidation
        ß-oxidation of monounsaturated fatty acids
        ß-oxidation of odd-chain length fatty acids
        ketone bodies

3/30/00 (discussion)
Quiz
Experiment 305 prelab

3/30/00 (lab)
Experiment 305

3/31/00: §13.4
        synthesis of saturated fatty acids
        elongation of saturated fatty acids
        desaturation of saturated fatty acids
        formation of TAG's and PL's

4/3/00: §10.6
        Gluconeogenesis
        Glycogenesis
        Glycogenolyis
        Prevention of futile cycling

4/5/00
Exam 3: Chapters 8, 10-13

4/6/00 (discussion)
Quiz
Experiment 304 prelab

4/6/00 (lab)
Experiment 304

4/7/00:  §15.1-15.4
        Photosynthesis
        Chloroplast structure
        Antenna molecules and special pairs
        Light Reactions

4/10/00:  §15.5-15.7
        Dark Reactions
        Regeneration
        C3 and C4 plants

4/12/00: §Chapter16
The Genetic Code

4/13/00 (discussion)
Quiz
Experiment 304 prelab

4/13/00 (lab)
Experiment 304

4/14/00: §Chapter17
Replication

4/17/00: §Chapter18
Transcription

4/19/00: §Chapter19.1, 19.2
Translation

4/20/00 (discussion)
Quiz
Experiment 304 prelab

4/20/00 (lab)
Experiment 304

4/21/00: §19.3
Initiation

4/24/00: §19.4
Elongation

4/26/00: §19.5-19.7
Termination

4/27/00 (discussion)
Quiz
Experiment 304

4/27/00 (lab)
Experiment 304

4/28/00: §Appendix C6
Molecular Biology

5/1/00: §Appendix C6
Molecular Biology

5/3/00: §Appendix C6
Faculty Rating
Molecular Biology
wrapup

5/4/00 (discussion)
Lab Exam II

5/4/00 (lab)
Check in equipment

5/5
Exam 5: Chapters 17-19

5/12
Standardized Comprehensive Final Examination:

Send any comments s to: twiese@fhsu.edu
Last modified January 12, 2000

Monday	Wednesday	Thursday Discussion	Thursday Lab	Friday
1/11	1/12 §1.2, 1.3 Introduction	1/13 Lab notebooks	1/13 Check out equipment	1/14 §1.3, 1.4 Additional background
1/17 No Class	1/18 §5.1 Monosaccharides	1/19 Quiz 1 Exp. 301 Prelab	1/19 Exp. 301 (due 2/11)	1/20 §5.2, 5.3 M/S Reactions, D/S
1/24 §5.4, 5.5 Polysaccharides	1/26 §6.1, 6.2 Structural lipids	1/27 Quiz 2 Exp 301 Prelab	1/27 Exp. 301 (due 2/11)	1/28 §6.3, 6.4 Other lipids and fcns
1/31 §6.5, 6.6 Membranes	2/2 §2.1 Amino acid structure	2/3 Quiz 3 Exp. 301 Prelab	2/3 Exp. 301 (due 2/11)	2/4 §2.2 Amino acid chemistry
2/7 §2.3-2.5 Peptide bond, peptides	2/9 Exam 1	2/10 Quiz 4 Exp. 302 Prelab	2/10 Exp. 302 (due 2/25)	2/11 §3.1 Protein classification
2/14 §3.2, 3.6 Protein 1^o structure	2/16 §3.3, 3.6 Protein 2^o structure	2/17 Quiz 5 Exp. 302 Prelab	2/17 Exp. 302 (due 2/25)	2/18 §3.5 Protein 3^o,4^o structure
2/21 §4.1, 4.2 Enzyme classification	2/23 §4.4 Coenzymes	2/24 Quiz 6 Exp. 303 Prelab	2/24 Exp. 303 (due 3/18)	2/25 Ch. 4 Enzyme Kinetics
2/28 Ch. 4 Enzyme active sites	2/29 Ch. 4 Enzyme Regulation	3/1 Quiz 7 Exp. 303 Prelab	3/1 Exp. 303 (due 3/18)	3/2 §7.1-7.4 Nucleic acid structure
3/6 §7.5, 7.6 Nucleic acid properties	3/8 Exam 2	3/9 Lab Exam 1 (301-303)	3/9 Exp. 303 (due 3/18)	3/10 Ch. 8, 9 Metabolism
3/13 §10.1-10.3 Glycolysis	3/15 §11.1, 11.3 TCA cycle	3/16 Quiz 8 Exp. 305 Prelab	3/16 Exp. 305 (due 4/8)	3/17 §11.4, 11.5 TCA cycle
3/20 Spring Break
3/27 §12.3-12.5 ETC and ox phos	3/29 §13.3 ß oxidation	3/30 Quiz 9 Exam 3	3/30 Exp. 305 (due 4/8)	3/31 §13.4 ß oxidation
4/3 §10.6 Carbohydrate synthesis	4/5	4/6 Quiz 10 Exp. 304 Prelab	4/6 Exp. 304 (due 5/6)	4/7 §15.1-15.4 Photosynthesis
4/10 §15.5-15.7 Photosynthesis	4/12 §16 The Genetic Code	4/13 Quiz 11 Exam 4	4/13 Exp. 304 (due 5/6)	4/14 §17 Replication
4/17 §18 Transcription	4/19 §19.1, 19.2 Translation: Preinitiation	4/20 Quiz 12 Exp. 304 Prelab	4/20 Exp. 304 (due 5/6)	4/21 §19.3 Initiation
4/24 §19.4 Elongation	4/26 §19.5-19.7 Termination	4/27 Quiz 13 Exp. 304 Prelab	4/27 Exp. 304 (due 5/6)	4/28 §App. C6 Molecular Biology
5/1 §App. C6 Molecular Biology	5/3 Wrap-up Faculty Evaluation	5/4 Lab Exam 2 (303-305)	5/4 Check in equipment	5/5 Exam 5
Standardized Comprehensive Final Examination: 10:30 AM Wednesday May 10, 2000 Room 112 TH