Chemistry 664 — Biochemistry II
Tentative Lecture Schedule — Spring 2008
This schedule is laid out in the following format:
Date: Reading Assignment (pages)
Topics covered
1/13: Chapter 13
Course Introduction
Types of Pathways (359-363)
1/15: Chapter 13
Thermodynamic Principles (364-373)
Phosphorylation potential
and ATP-driven reactions
1/20: Chapter 13
Reducing potential-driven
reactions
Energy exchange molecules
(373-394)
1/22: Chapter 14
Reactions of the glycolytic
pathway (400-414)
1/25: Chapter 14
Regulation and energetics
of the glycolytic pathway (400-414)
1/27: Chapter 14
Glycogenolysis (421-422,
428-432)
Common dietary disaccharides
are cleaved to monosaccharides which enter (424)
Other sugars lead into the
glycolytic pathway (422-423)
1/29: Chapter 14
The hexose monophosphate
shunt (436-438)
Uronic acid pathway
2/1: Chapter 15
Kreb's cycle (446-459)
2/3: Chapter 15
Regulation of Kreb's
cycle (467-473)
2/5: Chapter 18
Sites of the ETC (542-554)
2/8: Chapter 18
Mechanism of electron
flow (542-554)
Chemisosmotic theory (555-564)
Uncoupling protein (566-567)
2/10: Chapter 16
Overview of lipid metabolism
(479-482)
Reactions of ß-oxidation
(483-489)
Energetics (489-490)
Regulation (496)
2/12: Chapter 16
ß-Oxidation of unsaturated
fatty acids
ß-Oxidation of odd
chain length fatty acids (490-493 )
Ketone bodies (499-501)
2/15: Chapter 17
Overview of protein metabolism
(506-510)
Transport of ammonium ions
(511-517)
Urea cycle (517-521)
2/19: Chapter 17
Catabolism of amino acid
backbones (522-537)
2/21: Chapter 21
Catabolism of nucleotides
(727-730)
2/23: Chapter 19
Gluconeogenesis (- )
2/25: Chapter 19
Glycogenesis (-)
Starch and sucrose/lactose
synthesis (-)