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Inhibitors and Effectors

Agent Action Concentration to use stock conc. Solubility
Cytochalasin B Inhibits (Glc) transport 100 然 . ethanol
Phloridzin Inhibits (Glc) transport 0.5 mM . .
Phloretin Inhibits (Glc) transport 0.5 mM . .
Forskolin Increase [cAMP] 5-10 然 10 mM DMSO
PMA Increase [cAMP] 10-100 nM . .
L-PHA . 1 痢/mL . .
Bryostatin . low 10-100 pM
high 100 nM-1 然
. .
Pertussis Toxin G proteins 100 ng/mL for 18h . .
Okadaic acid Phosphatase 1 & 2A inhibitor 1-10 然 for 24h 100 然 DMSO
NH4Cl Acidify lysosomes 20 mM for 10 min . .
Isoproterenol . 1 然 . .
Sommatostatin . 100 nM . .
Actinomycin D RNA synthesis inhibitor 1-10 痢/mL . .
Cycloheximide protein synthesis inhibitor 100 然 . .
Streptolysin O pore-forming agent 1 痢/mL for 80min . .
Cypermethrin Phosphatase inhibitor 0.1 然 for 24 h . .
A23187 Ca2+ Ionophore . . .
Sorbinil Aldose reductase inhibitor 0.4 mM . .
Staurosporine Ser/Thr kinase inhibitor 100 nM 10 然 DMSO
Quinidine Ca2+ channel blocker 0.5 mM . Methanol
Verapamil Ca2+ channel blocker 0.5 mM . Methanol
Riampicin RNA polymerase inhibitor . . .
GTP[gamma]S stimulate adenylate cyclase 100 然 . .
MG132 preoteasome inhibitor 100 然 . DMSO
epoxomycin preoteasome inhibitor 40 然 . DMSO
clasto-lactacystin-beta-lactone, preoteasome inhibitor 40 然   DMSO
Cucurbitacin I I STAT3 inhibitor 0.1~10 nM 5 mg/mL DMSO
Wortmanin PI-3-kinase inhibitor ~50 nM    
bestatin methyl ester aminopeptidase inhibitor      
PD980059 MEK inhibitor ~100 µM    
phenylephrine a1-adrenergic receptor agonist      
         
         
         
         
         

Last Modified May 9, 2008

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