The development of knowledge necessary for the improvement
of the health and well-being of humans as well as other animals
requires in vitro experimentation with a wide variety of animal
species. Whenever U.S. Government agencies develop requirements
for testing, research, or training procedures involving the use
of vertebratimals, the following principles shall be considered;
and whenever these agencies actually perform or sponsor such procedures,
the responsible Institutional Official shall ensure that these
principles are adhered to:
I. The transportation, care, and use of animals
should be in accordance with the Animal Welfare Act (7 U.S.C.2131
et. seq.) and other applicable Federal laws, guidelines, and policies.
II. Procedures involving should be designed and
performed with due consideration of their relevance to human or
animal health, the advancement of knowledge, or the good of society.
III. The animals selected for a procedure should
be of an appropriate species and quality and the minimum number
required to obtain valid results. Methods such as mathematical
models, computer simulation, and in vitro biological systems
should be considered.
IV.
Proper use of animals, including the avoidance or minimization
of discomfort, distress, and pain when consistent with sound scientific
practices, is imperative. Unless the contrary is established,
investigators should consider that procedures that cause pain
or distress in human beings may cause pain or distress in other
animals.
V.
Procedures with animals that may cause more than momentary or
slight pain or distress should be performed with appropriate sedation,
analgesia, or anesthesia. Surgical or other painful procedures
should not be performed on unanesthetized animals paralyzed by
chemical agents.
VI.
Animals that would otherwise suffer severe or chronic pain or
distress that cannot be relieved should be painlessly killed at
the end of the procedure or, if appropriate, during the procedure.
VII.
The living conditions of animals should be appropriate for their
species and contribute to their health and comfort. Normally,
the housing, feeding, and care of all animals used for biomedical
purposes must be directed by a veterinarian or other scientist
trained and experienced in the proper care, handling, and use
of the species being maintained or studied. In any case, veterinary
care shall be provided as indicated.
VIII.
Investigators and other personnel shall be appropriately qualified
and experienced for conducting procedures on living animals. Adequate
arrangements shall be made for their in-service training, including
the proper and humane care and use of laboratory animals.
IX.
Where exceptions are required in relation to the provisions of
these Principles, the decisions should not rest with the investigators
directly concerned but should be made, with due regard to Principle
II, institutional animal care and use committee. Such exceptions
should not be made solely for the purposes of teaching or demonstration.
X.
Institutional Endorsement and PHS Approval
A.
Authorized Institutional Official
Name:
Dr. Larry Gould
Title: Provost
Address:
Fort
Hays State University
600
Park Street
Hays,
KS 67601-4099
Phone:
(913) 628-4241
Signature:
__________________________
Date:
______________
B.
PHS Approving Official
Name:
______________________________
Title:
_______________________________
Address:
____________________________
____________________________
____________________________
Phone:
____________________________
Signature:
_________________________
Date:
_____________________________
C.
Effective Date of Assurance: _________________
D.
Expiration Date of Assurance: ________________
